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Systematic Reviews in Health Care

Meta-analysis in Context

By Matthias Egger (Edited by), George Davey Smith (Edited by), Douglas Altman (Edited by)

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Format: Hardcover, 506 pages, 2nd Revised Edition
Other Information: 83
Published In: United Kingdom, 18 March 2000
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Table of Contents

Foreword Introduction: Rationale, potentials and promise of systematic review Part I: Systematic reviews of controlled trials Principles and procedures Problems and limitations Identifying randomised trials Assessing the quality of controlled clinical trials Obtaining individual patient data from randomised controlled trials Assessing the quality of reports of systematic reviews Part II: Investigating variability within and between studies Going beyond the grand mean Why and how sources of heterogeneity should be investigated Analysing the relationship between treatment benefit and underlying risk Investigating and dealing with publication and other biases Part III: Systematic review of observational studies Systematic reviews of observational studies Systematic reviews of prognostic studies Systematic reviews of evaluations of diagnostic studies Part IV: Statistical method and computer software Statistical methods of examining heterogeneity and combining results from several studies.. Choice of effect measure for binary outcomes Meta-analysis software Meta-analysis in STATA Part V: Using systematic reviews in practice Applying the results of systematic reviews at the bedside Numbers needed to treat derived from meta-analysis: pitfalls and cautions Using systematic reviews in clinical guidelines development Using systematic reviews for evidence based policy making Using systematic reviews for economic evaluation Using systematic reviews and registers of ongoing trials for scientific and ethical trial design.. Part VI: The Cochrane Collaboration The Cochrane Collaboration in the 20th Century The Cochrane Collaboration in the 21st Century: ten challenges and one reason whey they must be met Part VII: Future challenges Unresolved issues and future developments

EAN: 9780727914880
ISBN: 072791488X
Publisher: BMJ Books
Dimensions: 23.39 x 15.6 x 2.87 centimeters (0.73 kg)
Age Range: 15+ years
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