Table of Contents

I. Brain Gene Products.- 1. A Comparative Study of the Diversity of Gene Expression in Brain.- 2. Messenger RNA in the Brain.- 3. Gene Expression in the Mammalian Brain.- 4. Expression of Brain-Specific Proteins.- 5. Messenger RNA is Present in the Axoplasm of Squid Giant Axons.- II. Cloning and Expression of Brain Genes.- 6. Molecular Genetics of Tyrosine Hydroxylase.- 7. Analysis of Synapsin I and G-Substrate Gene Expression by cDNA Cloning and in situ Hybridization Histochemistry.- 8. The Expression of Microtubule Proteins During the Development of the Nervous System.- 9. Regulation of Expression of the Human Proenkephalin Gene in Heterologous Cell Systems.- 10. The Regulation of Proopiomelanocortin Gene Expression by Estrogen in the Rat Hypothalamus.- III. The Molecular Biology of Neurological Diseases.- 11. DNA Analysis of Duchenne and Becker Muscular Dystrophies.- 12. Genetic Analysis of the Fragile X-Mental Retardation Syndrome with Polymorphic DNA Markers.- 13. Brain Messenger RNA in Alzheimer’s Disease.- 14. The Effect of Trisomy-21 (Down’s Syndrome) on Brain Transcription.- IV. Brain DNA.- A. Neuronal Chromatin Structure and DNA Content.- 15. Neuronal Chromatin During Development.- 16. Post-Translational Modifications of Chromosomal Proteins in Neuronal and Glial Nuclei from Developing Rat Brain.- 17. DNA Content in Neurons.- B. Enzymes Related to DNA Metabolism.- 18. Enzymology of DNA Replication and Repair in Brain.- 19. Brain Dnases and their Functional Importance.- 20. Polyadp-Ribose Polymerase and ADP-Ribosylation Reaction.- C. DNA Turnover.- 21. DNA Synthesis and Cell Number Homeostasis in the Brain.- 22. Brain DNA Changes During Learning.- 23. Role of DNA in Brain Information Processing.- V. Special Lecture.- 24. RNA and Learning.- VI. Posters.- 25.Molecular Genetics of the Nerve Cell Adhesion Molecule N-Cam: Evidence for Multiple, Developmentally Regulated, MRNA Species.- 26. The Characterization of Cdnas Encoding Brain-Specific and Ubiquitous MRNA by Hybrid-Selected Translation.- 27. Opioid Peptide Precursors in the Amphibian xenopus Laevis.- 28. Sensitive Hybridization Techniques as Powerful Tools in Molecular Genetics to Identify Brain-Specific Gene Products.- 29. Molecular Cloning and Nucleotide Sequences of cDNA and Genomic DNA for the Rat Brain S-100 Protein.- Author Index.