Table of Contents

Introduction to RNA Vaccines.- Self-replicating RNA.- Self-replicating RNA Vaccine Delivery to Dendritic Cells.- Plant Expression of Trans-encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons.- RNActive® Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines.- Nucleoside Modified mRNA Vaccines for Infectious Diseases.- Generation and Evaluation of Prophylactic mRNA Vaccines against Allergy.- Measuring the Adjuvant Activity of RNA Vaccines.- Generation of Immunostimulating 130 nm Protamine-RNA Nanoparticles.- Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins.- Adjuvant-Enhanced mRNA Vaccines.- Enhanced Delivery of DNA or RNA Vaccines by Electroporation.- The European Regulatory Environment of RNA-Based Vaccines.- Discovery and Subtyping of Neo-Epitope Specific T-cell Responses for Cancer Immunotherapy: Addressing the Mutanome.- Considerations for Producing mRNA Vaccines for Clinical Trials.- Nonclinical Safety Testing of RNA Vaccines.- Immunotherapy of Uveal Melanoma: Vaccination Against Cancer.