Table of Contents

Section A Epidemiology.- 1 A woman’s view of the menopause.- 2 Epidemiology of the climacteric syndrome.- 3 Frequency and severity of menopausal symptoms.- 4 Physical changes associated with the post-menopausal years.- Section B Endocrinology.- Endocrinology (Part 1).- 5 Endocrine changes associated with the menopause and post-menopausal years.- 6 Intensive steroid and protein hormone profiles on post-menopausal women experiencing hot flushes, and a group of controls.- Endocrinology (Part 2).- 7 Pharmacology of natural and synthetic estrogens.- 8 Estrogen target organs and receptor.- Section C Psychological Aspects.- 9 Emotional response to the menopause.- 10 Psychiatric aspects of the menopause.- 11 Psychological changes following hormonal therapy.- 12 Estrogens, plasma tryptophan levels in perimenopausal patients.- 13 Double blind psychometric studies on the effects of natural estrogens on post-mcnopausal women.- 14 Double blind cross-over study of estrogen replacement therapy.- Section D Lipid Metabolism.- 15 The menopause and coronary heart disease.- 16 The effects of ethinyl estradiol and conjugated equine estrogens on plasma lipids in oophorectomized women.- 17 The effect of synthetic and natural estrogens on glucose tolerance, plasma insulin and lipid metabolism in post-menopausal women.- Section E Calcium Metabolism.- 18 Post-menopausal changes in calcium and phosphorus metabolism.- 19 Osteoporosis and its relation to estrogen deficiency.- Section F Skin.- 20 The effect of estrogens on the skin.- 21 Effect of castration and peroral estradiol valerate and estriol succinate therapy on the epidermis.- 22 The correlation of menopausal symptoms with cytohormonal status.- 23 Cervical colposcopic changes associated with the menopause.- Section G Urinary Tract.- 24Post-menopausal changes in micturition habits and in urine flow and urethral pressure studies.- 25 The effect of estrogens on bladder function in the female.- 26 Urethral profile studies on menopausal women and the effects of estrogen treatment.- Section H Risks of Estrogen Therapy.- 1: Thromboembolism.- 27 A double blind cross-over study with conjugated equine estrogens on blood clotting.- 28 Effects of synthetic and natural estrogens on the coagulation system in post-menopausal women.- 2: Cancer.- 29 The effects of estrogen replacement therapy on the risk of cancer during the post-menopausal years.- 30 Estrogens and breast cancer.- Section I Therapeutic Problems.- 31 The premature menopause.- 32 The rationale of operative removal of the ovaries at hysterectomy.- 33 Contra-indications to estrogen therapy and management of the menopausal syndrome in these cases.- 34 Hormone implants in the climacteric syndrome.- Section J Management of The Menopause.- 35 A European viewpoint.- 36 An English viewpoint.- 37 Menopause—an American view.- 38 A dissident viewpoint.- 39 Financial implications of hormone replacement, therapy.

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