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Table of Contents

Tribute to John T. Reeves.- 1. John T. Reeves, MD.- From Genes to the Bedside.- 2. Genetic lessons from high altitude.- 3. Genes, environment, and exercise.- 4. Skeletal muscle angiogenesis.- 5. Leukocyte-endothelial interactions in environmental hypoxia.- Training at Altitude for Sea Level Performance.- 6. Hypoxia training for sea-level performance.- 7. The effects of altitude training are mediated primarily by acclimatization, rather than by hypoxic exercise.- High Altitude Pulmonary Edema.- 8. Update: High altitude pulmonary edema.- Comparative Biology.- 9. Phylogenetic comparison and artificial selection.- 10. Genetic and environmental adaptation in high altitude natives.- 11. Common themes of adaptation to hypoxia.- Erythropoietin.- 12. Biology of erythropoietin.- 13. Lessons to better understanding of hypoxia sensing.- 14. Erythropoietin use and abuse.- Mountain Medicine.- 15. Mountaineering in thin air.- 16. Weight loss at high altitude.- Stress Proteins and Hypoxia.- 17. The heme oxygenase system and cellular defense mechanisms.- 18. Hypoxia-inducible factor in brain.- Transepithelial Sodium Transport.- 19. Proton-gated cation channels — neuronal acid sensors in the central and peripheral nervous system.- 20. Structure function relationships of ENaC and its role in sodium handling.- 21. Transepithelial sodium and water transport in the lung.- Advances in Cardiorespiratory Control in Hypoxia.- 22. Is ventilatory acclimatization to hypoxia a phenomenon that arises through mechanisms that have an intrinsic role in the regulation of ventilation at sea level?.- 23. Roles of adenosine and nitric oxide in skeletal muscle in acute and chronic hypoxia.- 24. The pVHL-HIF-1 system.- Frontiers in Hypoxia Research.- 25. Interval hypoxic training.- 26. Gene transfer andmetabolic modulators as new therapies for pulmonary hypertension.- 27. Chronic mountain sickness.- 28. International Working Group for Chronic Mountain Sickness.- 29. Late and Amended Abstracts.