Table of Contents

PRINCIPLES AND MECHANISMS. Principles of Developmental Toxicology. Mechanisms of Developmental Toxicology. Pathogenesis of Abnormal Development. Maternally-Mediated Effects on Development. Paternally-Mediated Effects on Development. Comparative Embryology. HAZARD ASSESSMENT. Developmental Toxicity Testing - Single and Multiple Generation Test Methodology. Nonclinical Juvenile Toxicity Testing -- Methodology and Data Evaluation. Testing for Reproductive Toxicity in the Male and Female and Evaluation of the Data. Endocrine Disruption - Testing and Data Evaluation. Role of Xenobiotic Metabolism in Developmental Toxicity. Toxicokinetics. Cellular, Biochemical, and Molecular Techniques. Genomics and Proteomics. In Vitro Mechanistic Studies. Statistical Analysis. Quality Control - GLP for Toxicologists. Regulatory Test Guidelines. Epidemiologic Techniques in Development and Reproductive Toxicology. Risk Assessment - EPA Approach. Risk Assessment - FDA Approach. Appendices.

About the Author

Ronald D. Hood is a Toxicology Consultant at Ronald D. Hood & Associates and works at the University of Alabama, Tuscaloosa, USA.

Reviews

"This is a great foundation book for trainees pursuing research in reproductive toxicology and serves as the perfect reference during the course of study. The field of reproductive toxicology is changing and this update is critical and mostly timely."
—Doody's Review Service"It is one of the most comprehensive and definitive publications in the field and should be a mandatory addition to the libraries of students, researchers, and regulators alike in the field of reproductive and developmental toxicology."
—International Journal of Toxicology