Sriganesh Srihari is a Senior Research Fellow with
the Institute for Molecular Bioscience at The University of
Queensland, Australia. He has a background in computer science
(having received a Ph.D. in 2012 from National University of
Singapore) and has worked extensively on graph (network) and
combinatorial algorithms and in applying these to large omics
datasets in biomedicine. He has devised systems-biology models to
integrate ""multiomics"" datasets spanning genomics, RNAseq, and
proteomics (protein-protein interaction) with clinical profiles to
decipher molecular-clinical associations and identify new
therapeutic targets in cancers. He has published in leading
journals in the field including Bioinformatics, BMC Systems
Biology, Biology Direct, Molecular Biosystems, and Nucleic Acids
Research. He has closely collaborated with experimental biologists
and has contributed to joint publications in Oncogene (Nature
Publishing), Trends in Pharmacological Sciences (Cell Press), and
Molecular Oncology. His postdoctoral work on cancer network models
was highlighted in International Innovation (Healthcare issue,
2014), a Research Media periodical. His recent computational
approach MutExSL (Biology Direct, 2015), co-authored with Limsoon
Wong, for predicting synthetic-lethal targets by mining mutually
exclusive genetic alterations in cancers was presented at the San
Antonio Breast Cancer Symposium 2015 (San Antonio, Texas, USA), for
which he won an American Association for Cancer Research
(AACR)—Susan G.Komen for the Cure(R) Scholar-in-training Award. He
serves on the Editorial Board for the cancer bioinformatics theme
of Scientific Reports, and is a Guest Editor for Methods. Srihari
has recently moved to the South Australian Health and Medical
Research Institute, Australia, as a Senior Research Scientist. He
is also an Adjunct Senior Lecturer with the School of Computer
Science, Engineering, and Mathematics at Flinders University,
Australia.
Chern Han Yong is a Research Fellow in the Program
in Cancer and Stem Cell Biology and the Centre for Computational
Biology at the Duke-NUS Medical School, Singapore. He currently
works on cancer genomics and epigenomics, and is particularly
interested in the role of aberrant DNA methylation in
carcinogenesis. He obtained his Ph.D. in computational biology from
the National University of Singapore, where he researched the
challenges of predicting protein complexes from high-throughput
protein-protein interaction data. He obtained his M.Sc. in 2004 and
B.Sc. in 2000 in computer science from the University of Texas at
Austin, where he worked on neural networks, genetic algorithms, and
the evolution of multi-agent cooperative behavior.
Limsoon Wong is the Kwan-Im-Thong-Hood-Cho-Temple
Chair Professor in the Department of Computer Science and a
professor in the Department of Pathology at the National University
of Singapore. Before that, he was the Deputy Executive Director for
Research at A*STAR's Institute for Infocomm Research. He currently
works mostly on knowledge discovery technologies and their
application to biomedicine. He has also done, especially in the
earlier part of his career, significant research in database query
language theory and finite model theory, as well as significant
development work in broad-scale data integration systems. He is a
Fellow of the ACM, inducted for his contributions to database
theory and computational biology. Some of his awards include the
2003 FEER Asian Innovation Gold Award, for his work on treatment
optimization of childhood leukemias, and the ICDT 2014 Test of Time
Award, for his work on naturally embedded query languages. He
serves/served on the editorial boards of Journal of Bioinformatics
and Computational Biology, Bioinformatics, Biology Direct, Drug
Discovery Today, IEEE/ACM Transactions on Computational Biology and
Bioinformatics, Genomics Proteomics & Bioinformatics, Journal of
Biomedical Semantics, Methods, Scientific Reports, Information
Systems, and IEEE Transactions on Big Data. He is also an ACM Books
Area Editor. He received his B.Sc. (Eng.) in 1988 from Imperial
College London and his Ph.D. in 1994 from the University of
Pennsylvania.
Ask a Question About this Product More... |