Table of Contents

Contributors.
Preface.


1. Essential Elements of a Proteomics Laboratory (Daniel C.
Liebler).


2. Mass Spectrometry Tools for Proteomics (Li-Rong Yu, Ming
Zhou, Thomas P. Conrads, and Timothy D. Veenstra).


3. Gel-Based Proteomics: An Essential Core Technology in
Translational Cancer Research (Julio E. Celis, Irina Gromova, Jose
Moreira, Tereza Cabezo, Fritz Rank, and Pavel Gromov).


4. 2D Gel-Based Proteomic Analysis of Cancer (Sam Hanash).


5. Analysis of Protein Posttranslational Modifications and
Protein Adducts (Daniel C. Liebler).


6. Bioinformatics Tools for Proteomics (Daniel C. Liebler and
David B. Friedman).


7. Tissue Profiling and Imaging by Matrix-Assisted Laser
Desorption Ionization Mass Spectrometry (Robert L. Caldwell and
Richard M. Caprioli).


8. SELDI-TOF Applications for Cancer and Toxicity Detection
(Emanuel F. Petricoin and Lance A. Liotta).


9. Protein Microarrays: Applications for Discovery and
Quantitation (Virginia Espina, Julia Wulfkuhle, Emanuel F.
Petricoin III, and Lance A. Liotta).


10. Protein Arrays for Clinical Proteomics and Signal
Transduction Profiling (Fiona Simpkins, Victoria Espina, Edwin
Posadas, Emanuel F. Petricoin III, Lance Liotta, and Elise
Kohn).


11. Tissue Microarrays in Basic Cancer Research (Stephen M.
Hewitt).


12. Structural Proteomics: High Throughput Structure
Determination of Whole Organism Genomes (Demetrios T.
Braddock).


Index.

About the Author

Dr. Daniel C. Liebler is Professor, Department of Pharmacology and Toxicology, and Director, Southwest Environmental Health Sciences Center at the University of Arizona College of Pharmacy. He is also Director of the Toxicology Training Program and a member of the Arizona Cancer Center, as well as the author of Introduction to Proteomics (2001).

Reviews

"The book achieves its goal of reader education for developing a cancer proteomics project." (Biotechnology Focus, November 2005)