Table of Contents

Part 1 General Considerations in Clinical Medicine

Part 2 Cardinal Manifestations and Presentation of Diseases

Section 1 Pain

Section 2 Alterations in Body Temperature

Section 3 Nervous System Dysfunction

Section 4 Disorders of Eyes, Ears, Nose, and Throat

Section 5 Alterations in Circulatory and Respiratory Functions

Section 6 Alterations in Gastrointestinal Function

Section 7 Alterations in Renal and Urinary Tract Function

Section 8 Alterations in Sexual Function and Reproduction

Section 9 Alterations in the Skin

Section 10 Hematologic Alterations

Part 3 Genes, the Environment, and Disease

Part 4 Regenerative Medicine

Part 5 Aging

Part 6 Nutrition and Weight Loss

Part 7 Oncology and Hematology

Section 1 Neoplastic Disorders

Section 2 Hematopoietic Disorders

Section 3 Disorders of Hemostasis

Part 8 Infectious Diseases

Section 1 Basic Considerations in Infectious Diseases

Section 2 Clinical Syndromes: Community-Acquired Infections

Section 3 Clinical Syndromes: Health Care–Associated Infections

Section 4 Approach to Therapy for Bacterial Diseases

Section 5 Diseases Caused by Gram-Positive Bacteria

Section 6 Diseases Caused by Gram-Negative Bacteria

Section 7 Miscellaneous Bacterial Infections

Section 8 Mycobacterial Diseases

Section 9 Spirochetal Diseases

Section 10 Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae

Section 11 Viral Diseases: General Considerations

Section 12 Infections Due to DNA Viruses

Section 13 Infections Due to DNA and RNA Respiratory Viruses

Section 14 Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses

Section 15 Infections Due to RNA Viruses

Section 16 Fungal Infections

Section 17 Protozoal and Helminthic Infections: General Considerations

Section 18 Protozoal Infections

Section 19 Helminthic Infections

Part 9 Terrorism and Clinical Medicine

Part 10 Disorders of the Cardiovascular System

Section 1 Introduction to Cardiovascular Disorders

Section 2 Diagnosis of Cardiovascular Disorders

Section 3 Disorders of Rhythm

Section 4 Disorders of the Heart

Section 5 Coronary and Peripheral Vascular Disease

Part 11 Disorders of the Respiratory System

Section 1 Diagnosis of Respiratory Disorders

Section 2 Diseases of the Respiratory System

Part 12 Critical Care Medicine

Section 1 Respiratory Critical Care

Section 2 Shock and Cardiac Arrest

Section 3 Neurologic Critical Care

Section 4 Oncologic Emergencies

Part 13 Disorders of the Kidney and Urinary Tract

Part 14 Disorders of the Gastrointestinal System

Section 1 Disorders of the Alimentary Tract

Section 2 Liver and Biliary Tract Disease

Section 3 Disorders of the Pancreas

Part 15 Immune-Mediated, Inflammatory, and Rheumatologic Disorders

Section 1 The Immune System in Health and Disease

Section 2 Disorders of Immune-Mediated Injury

Section 3 Disorders of the Joints and Adjacent Tissues

Part 16 Endocrinology and Metabolism

Section 1 Endocrinology

Section 2 Reproductive Endocrinology

Section 3 Obesity, Diabetes Mellitus, and Metabolic Syndrome

Section 4 Disorders of Bone and Mineral Metabolism

Part 17 Neurologic Disorders

Section 1 Diagnosis of Neurologic Disorders

Section 2 Diseases of the Central Nervous System

Section 3 Nerve and Muscle Disorders

Section 4 Chronic Fatigue Syndrome

Section 5 Psychiatric and Addiction Disorders

Part 18 Poisoning, Drug Overdose, and Envenomation

Part 19 Disorders Associated with Environmental Exposures

APPENDIX: Laboratory Values of Clinical Importance

Index

About the Author

Dennis L. Kasper, MD, MA (Hon)William Ellery Channing Professor of MedicineProfessor of Microbiology and Molecular GeneticsExecutive Dean for Academic ProgramsHarvard Medical SchoolDirector, Channing LaboratoryDepartment of MedicineBrigham and Women’s Hospital Anthony S. Fauci, MDChief, Laboratory of ImmunoregulationDirector, National Institute of Allergy and Infectious DiseasesNational Institutes of Health. In 2008, Dr. Fauci was awarded the Presidential Medal of Freedom, the Nation's highest civil award. Stephen L. Hauser, MDChairman and Betty Anker Fife ProfessorDepartment of NeurologyUniversity of California, San Francisco Dan L. Longo, MDScientific DirectorNational Institute on AgingNational Institutes of HealthBethesda, Maryland C.F. Kettering Professor of Medicine, Chief, Division of Endocrinology, Metabolism and Molecular Medicine Northwestern University Medical School, Chicago, IL. Hersey Professor of the Theory and Practice of Medicine, Harvard Medical School; Chairman, Department of Medicine; Physician-in-Chief, Brigham and Women’s Hospital, Boston, Massachusetts