Chapter 1. Introduction to the Study of Epigenetics
Chapter 2. The Basis of the Transcription Process
Chapter 3. DNA Packaging and Chromatin Architecture
Chapter 4. Modifying the Structure of Chromatin
Chapter 5. DNA Methylation
Chapter 6. Post-Translational Modification of Histones
Chapter 7. Histone Modification Machinery
Chapter 8. Locus-Specific Control of Histone-Modifying Enzyme
Action
Chapter 9. Epigenetic Control of Cell-Specific Gene Expression
Chapter 10. Epigenetic Control of the Mitotic Cell Cycle
Chapter 11. The Epigenetic Basis of Gene Imprinting
Chapter 12. Epigenetic Control of Cellular Differentiation
Chapter 13. Reversibility of Epigenetic Modification Patterns
Chapter 14. Epigenetic Predisposition to Disease and
Imprinting-Based Disorders
Chapter 15. Epigenetics of Memory, Neurodegeneration, and Mental
Health
Chapter 16. Epigenetics of Cancer
"The author has made a very thorough presentation of several areas
within the field of epigenetics. The material has been presented in
a comprehensive, well-organized and understandable manner. He
allows the reader to gain a strong foundation of each subject area
by including detailed introductory sections. The coverage of the
topics will allow the reader to obtain both general knowledge and
also more detailed understanding of the regulating mechanisms
involved in epigenetic changes and the consequences of those
changes. The content is also relevant to current trends in the
field of epigenetics and includes reviews of disease states related
to epigenetics, such as cancer, which are actively being
researched."- WhatIsEpigenetics
"Armstrong’s Epigenetics textbook is not only timely but also
important for introducing scientists, new and seasoned, to the
ever-evolving world of epigenetics."
- The Quarterly Review of Biology, 2016, Vol. 91, No. 2"The author
has made a very thorough presentation of several areas within the
field of epigenetics. The material has been presented in a
comprehensive, well-organized and understandable manner. He allows
the reader to gain a strong foundation of each subject area by
including detailed introductory sections. The coverage of the
topics will allow the reader to obtain both general knowledge and
also more detailed understanding of the regulating mechanisms
involved in epigenetic changes and the consequences of those
changes.The content is also relevant to current trends in the field
of epigenetics and includes reviews of disease states related to
epigenetics, such as cancer, which are actively being
researched."
- WhatIsEpigenetics"In summary, Epigenetics provides a convincing
overview of epigenetic mechanisms at the molecular and cellular
levels. Clearly, such mechanisms are likely to be relevant to many
complex human diseases, but the details remain to be elucidated.
The enduring impression taken away from this book is of a
spectacularly complex and dynamic interplay among different
epigenetic factors in the regulation of gene expression and
cellular differentiation. Any researcher interested in these
phenomena should find this textbook an excellent resource."
- International Journal of Epidemiology, 2015, Vol. 44, No. 4
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